Assassin Artemis Entreri whisks his kidnap victim, Regis, south to Calimport. If Entreri's employer Pasha Pook can control the magical panther Guenhyvar, Regis will die in a real game of cat and mouse. The companions from Icewind Dale battle pirates, brave the deserts of Calimshan, and fight mosters from other planes to rescue their friend...and themselves.